DAI Cheng-en;LI Hai-long;HE Xiao-ping;ZHENG Fen-fen;ZHU Hua-liu;LIU Liang-feng;DU Wei;

• 1:Zhejiang Yalin Biological Technology Co.
• 2:Ltd.
• 3:Research Institute of Subtropical Forestry
• 4:Chinese Academy of Forestry

Abstract：

The pharmacological activity of active ingredients from Chinese medicine depends greatly on the microecological environment of probiotics in the human body.After effective ingredients from traditional Chinese medicines are metabolized or biotransformed by probiotics,their metabolites can increase pharmacological activity,and can be absorbed more easily to improve the bioavailability.Therefore,the combination of Chinese medicines with probiotics is the innovation point in R&D of functional food and Chinese medicines,and also a new thinking for the modernization of Chinese medicine.This review summarizes and analyses the research progress on metabolism effects of gut microbiota on Chinese medicines components,the regulating effect of effective ingredients from Chinese medicine on intestinal probiotics,the application status of probiotics in traditional Chinese medicines,and the main problems and prospects in the research and development of Chinese medicines products with probiotic,aiming to provide theoretical guidance and practical value for the fermentation engineering of Chinese herbal medicine.

Key Words： traditional Chinese medicine;effective ingredients;pharmacological activity;probiotics;functional foods;metabolism

Abstract:

Keywords:

Foundation: 杭州市富阳区科技计划项目(2016NK002)

Authors: DAI Cheng-en;LI Hai-long;HE Xiao-ping;ZHENG Fen-fen;ZHU Hua-liu;LIU Liang-feng;DU Wei;

DOI: 10.19540/j.cnki.cjcmm.20170919.012

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